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On the basis of evaluations by the editors and peer reviewers, submitted manuscripts are either rejected or returned to authors with suggestions for improvement through revision. Authors should realize that a request for revision does not guarantee acceptance, because revised manuscripts are subject to editorial review and may also have additional peer review. Several rounds of review and revision may occur before a final decision is reached. Acceptance of manuscripts expressing viewpoints, perspectives, or opinions may be based solely on editorial review, but reports of original data and other major articles almost always undergo peer review, statistical review, and revision ...Less