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Abstract and Introduction

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.022.594
Item type: 
section
UPDATE: We will discontinue using quotation marks to identify parts of an article, but retain the capitalization; eg, This is discussed in the Methods section (not the “Methods” section). This change ... More

Case Series

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.022.605
Item type: 
section
A case series describes characteristics of a group of patients with a particular disease or patients who have undergone a particular procedure. A case series may also involve observation of larger units ... More

Case-Control Studies

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.022.604
Item type: 
section
Case-control studies, which are always retrospective, compare those who have had an outcome or event () with those who have not (). Cases and controls are then evaluated for exposure to various and thus ... More

Cohort Studies

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.022.603
Item type: 
section
A prospective cohort study follows a group or of individuals who are initially free of the outcome of interest. Individuals in a cohort generally share some underlying characteristic, such as age, sex, ... More

Cost-effectiveness Analysis, Cost-Benefit Analysis

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.021.281
Item type: 
section
Although a treatment or screening technique may be shown to be effective in an RCT, recommending it in general practice would not necessarily be rational. Such interventions may be prohibitively expensive, ... More

Crossover Trials

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.022.600
Item type: 
section
In a crossover trial, participants receive more than 1 of the treatments under investigation, usually in a randomly determined sequence, and with a prespecified amount of time (a ) between sequential ... More
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Discussion (Comment)

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.022.597
Item type: 
section
Whether the hypothesis was supported or refuted by the results should be addressed. The study result should be placed in context of published literature. The limitations of the study should be discussed, ... More

Equivalence and Noninferiority Trials

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.022.601
Item type: 
section
It is sometimes desirable to compare a less expensive treatment or intervention against a treatment or intervention that is already known to be effective. In these cases, it would be unethical to expose ... More
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Glossary of Statistical Terms

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.021.285
Item type: 
section
UPDATE: We will discontinue using quotation marks to identify parts of an article, but retain the capitalization; eg, This is discussed in the Methods section (not the “Methods” section). This change ... More
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The Manuscript: Presenting Study Design, Rationale, and Statistical Analysis

Margaret A. Winker and Stephen J. Lurie

in AMA Manual of Style: A Guide for Authors and Editors (10th edition)

Print Publication Year: 
2007
Published Online: 
2009
DOI: 
10.1093/jama/9780195176339.021.277
Item type: 
section
Each portion of the manuscript should contribute to the reader’s understanding of why and how the study was done and should help persuade the reader that (1) the hypothesis or study question is clearly ... More

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