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Study Design and Statistics

Margaret A. Winker

and Stephen J. Lurie

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Principal authors: Margaret A. Winker, MD; updated by Stephen J. Lurie, MD, PhD

Dedicated to George W. Brown, MD, whose patient but persistent teaching led to this chapter.

Many thanks to John C. Bailar III, MD, PhD; Thomas B. Cole, MD, MPH; Theodore Colton, ScD; Peter Cummings, MD, PhD; Robert M. Golub, MD; and Naomi Vaisrub, PhD, for reviewing prior versions of this chapter.

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