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Acronyms and Initialisms 

Acronyms and Initialisms

Brenda Gregoline

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Acronyms and Initialisms

Do not capitalize the words from which an acronym or initialism is derived (see 14.0, Abbreviations).

prostate-specific antigen (PSA)

enzyme-linked immunosorbent assay (ELISA)

Exception: When the words that form the acronym or initialism are proper names, use capitals as described in 10.3.9, Proper Nouns, Official Names:

National Institute of Mental Health (NIMH)

When there has been a “stretch” to create a study name or the name of a writing group that makes sense, is easy to say, and somehow relates to the name of the group, but where the first letters of the major words do not match the acronym, do not use unusual capitalization to indicate how the study name was derived. Expanded study or group-authorship names use normal JAMA and the Archives Journals capitalization style.

Evaluation of Platelet IIb/IIIa Inhibitor for Stenting (EPISTENT)

Enhanced Suppression of the Platelet IIb/IIIa Receptor With Integrilin Therapy (ESPRIT)

Clopidogrel as Adjunctive Reperfusion Therapy (CLARITY)

Clopidogrel in Unstable Angina to Prevent Recurrent Events (CURE)

c7E3 Fab Antiplatelet Therapy in Unstable Refractory Angina (CAPTURE)

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