Studies of Diagnostic Tests - AMA Manual of Style

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Studies of Diagnostic Tests 

Study Design and Statistics

Margaret A. Winker

and Stephen J. Lurie

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PRINTED FROM AMA MANUAL OF STYLE ONLINE ( © American Medical Association, 2009. All Rights Reserved. Under the terms of the license agreement, an individual user may print out a PDF of a single chapter of a title in AMA Manual of Style Online for personal use (for details see Privacy Policy). date: 29 November 2015

Correct treatment depends on accurate diagnosis. Diagnostic tests may include simple procedures such as physical signs or physical examination, as well as blood tests and radiologic imaging. Few diagnostic tests, however, can be relied on to yield accurate diagnoses 100% of the time. Thus, it is important to study the performance of diagnostic tests. Bossuyt et al stated: Exaggerated and biased results from poorly designed and reported diagnostic studies can trigger their premature dissemination and lead physicians into making incorrect treatment decisions. A rigorous evaluation process of diagnostic tests before introduction into clinical practice could not only reduce the number

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