Significant Digits and Rounding Numbers - AMA Manual of Style

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Significant Digits and Rounding Numbers 

Study Design and Statistics

Margaret A. Winker

and Stephen J. Lurie

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Significant Digits and Rounding Numbers

When numbers are expressed in scientific and biomedical articles, they should reflect the degree of accuracy of the original measurement. Numbers obtained from mathematical calculations should be rounded to reflect the original degree of precision.

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