Online-Only (Supplementary) Material

□ 1. Review manuscript submission instructions on our Web-based submission and review system (http://manuscripts.jama.com).

□ 2. Include a cover letter as an attachment.

□ 3. Designate a corresponding author and provide a complete postal/mail address, telephone and fax numbers, and e-mail address.

□ 4. Provide first and last names, degrees, e-mail addresses, and institutional affiliations for any coauthors.

□ 5. On the title page, include a word count for text only, exclusive of title, abstract, references, tables, and figure legends.

□ 6. Provide an abstract that conforms to the required abstract format.

□ 7. Double-space manuscript and leave right margins unjustified (ragged).

□ 8. Check all references for accuracy and completeness. Put references in proper format in numerical order, making sure each is cited in sequence in the text.

□ 9. Include a title for each table and figure (a brief, succinct phrase, preferably no longer than 10–15 words) and explanatory legend as needed.

□ 10. Have each author read, complete, and sign the Authorship Form with statements of authorship responsibility, criteria, and contributions; financial disclosure; and copyright transfer. After submission, add the manuscript number to the top of each author form and send in the author forms by mail or fax to the editorial office.

□ 11. Indicate specific contributions from each author (see authorship checklist on Authorship Form).

□ 12. Include statement signed by corresponding author that written permission has been obtained from all persons named in the Acknowledgment.

□ 13. For reports of original data, include statement from at least 1 author that she or he “had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.”

□ 14. Include research or project support/funding in the Acknowledgment.

□ 15. Also in the Acknowledgment, specify the role of the funder(s) or sponsor(s) in each of the following: design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.

□ 16. Include written permission from each individual identified as a source for personal communication or unpublished data.

□ 17. If appropriate, include information on institutional review board/ethics committee approval or waiver and informed consent.

□ 18. Reprinted tables and figures are discouraged. Original material should be provided, except under extraordinary circumstances.

□ 19. Include informed consent forms for identifiable patient descriptions, photographs, videos, and pedigrees.

□ 20. For clinical trials, add the clinical trial identification number and the URL of the registration site.