Stereoisomers - AMA Manual of Style

Subscriber Login

Forgotten your password?

Page of



Margaret A. Winker

Page of

PRINTED FROM AMA MANUAL OF STYLE ONLINE ( © American Medical Association, 2009. All Rights Reserved. Under the terms of the license agreement, an individual user may print out a PDF of a single chapter of a title in AMA Manual of Style Online for personal use (for details see Privacy Policy). date: 25 November 2015

Some molecules may occur with identical atoms in the same sequence but with different spatial arrangements. These are referred to as stereoisomers. A stereoisomer that is nonsuperimposable on its mirror image is chiral, and an atom with 4 different substituents is a chiral center; the 2 mirror images are enantiomers. An equal mixture of the 2 enantiomers is racemic. Generally only 1 enantiomer is biologically active, as in the case of ibuprofen. In some cases, one enantiomer may be biologically beneficial while the other enantiomer is harmful. For example, one enantiomer of thalidomide is a beneficial drug whereas the other

Access to the complete content on AMA Manual of Style requires a subscription or purchase. Public users are able to search the site and view the abstracts and keywords for each book and chapter without a subscription.

Please subscribe or login to access full text content.

If you have purchased a print title that contains an access token, please see the token for information about how to register your code.

For questions on access or troubleshooting, please check our FAQs, and if you can't find the answer there, please contact us.