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Cheryl Iverson

in AMA Manual of Style: A Guide for Authors and Editors (11 ed.)

Print Publication Year: 
Feb 2020
Published Online: 
Feb 2020
Item type: 
Immunoglobulins are the Y-shaped glycoproteins on the surface of B cells (see, B Lymphocytes) that can be secreted as antibodies in response to an antigenic stimulus (any molecule or composition of molecules from pathogens: bacterium, virus, parasite, or from transplanted organ that are recognized by immunoglobulin). Secreted antibodies can bind specifically to their antigens and in some cases can neutralize pathogens. The immunoglobulins were first recognized by serum electrophoresis and, because they were localized to the electrophoretic gamma zone, were originally referred to as ...