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Nonrandomized Trials.  

Edward H. Livingston

in AMA Manual of Style: A Guide for Authors and Editors (11th ed.)

Print Publication Year: 
Feb 2020
Published Online: 
Feb 2020
DOI: 
10.1093/jama/9780190246556.003.0019.022.0012
Item type: 
section
A nonrandomized trial prospectively assigns groups or populations to study the efficacy or effectiveness of an intervention but the assignment to the intervention occurs through self-selection or administrator selection rather than through randomization. Control groups can be historical, concurrent, or both. This design is sometimes called a quasi-experimental design. Reports of these trials should follow the Transparent Reporting of Evaluations With Nonrandomized Designs (TREND) reporting guideline (...

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