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Comparative Effectiveness Studies.  

Edward H. Livingston

in AMA Manual of Style: A Guide for Authors and Editors (11th edn)

Print Publication Year: 
Feb 2020
Published Online: 
Feb 2020
DOI: 
10.1093/jama/9780190246556.003.0019.022.0018
Item type: 
section
A comparative effectiveness study compares different interventions or strategies to prevent, diagnose, treat, and monitor health conditions to determine which work best for which patients and under what circumstances and which are associated with the greatest benefits and harms. Comparative effectiveness studies evaluate how effective existing therapies are in achieving various clinical outcomes. The outcomes may be tested by conducting RCTs or by observational analysis of existing data. Thus, from a study design perspective, they differ little from conventional studies of clinical efficacy....

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